| Date | Team | |
|---|---|---|
| 04/21/22 | Sussex County Miners | Esquerra, Trevin released |
| 04/21/22 | Sussex County Miners | Struble, LT Retired |
| 04/20/22 | Evansville Otters | Armstrong, Andy signed |
| 04/18/22 | Evansville Otters | Armstrong, Andy acquired in trade from outside league Ogden (Pioneer) |
| 04/18/22 | Evansville Otters | Portela, Polo traded to outside league Ogden (Pioneer) |
| 04/11/22 | Sussex County Miners | Rose, Joey released |
| 04/11/22 | Sussex County Miners | Carrizales, Omar released |
| 04/09/22 | Sussex County Miners | Miller Sr., Jalen traded to outside league Lexington Legends of ALPB |
| 04/08/22 | Sussex County Miners | Herrmann, Max placed on protected list |
| 04/08/22 | Evansville Otters | Gilliland, Jacob signed |
| 04/05/22 | Trois-Rivières Aigles | Martinez, Yareb signed |
| 04/04/22 | Florence Yalls | Hockin, Chad traded to outside league to the Long Island Ducks |
| 04/04/22 | Ottawa Titans | Cable, Tanner placed on inactive list |
| 04/04/22 | Ottawa Titans | Quiggle, Kona traded to outside league to the Sioux Falls Canaries |
| 04/04/22 | Ottawa Titans | Whatley, Kevin traded to outside league to the Missoula PaddleHeads |
| 04/03/22 | Lake Erie Crushers | Wells, Kenny signed |
| 04/01/22 | Trois-Rivières Aigles | Hegadoren, Eric signed |
| 04/01/22 | Trois-Rivières Aigles | Harmon, Bradley signed |
| 04/01/22 | Trois-Rivières Aigles | Graffeo, Carlo signed |
| 04/01/22 | Evansville Otters | Nightengale, Drake signed |
| 04/01/22 | Schaumburg Boomers | Skinner, Marshall acquired in trade from outside league From Gary SouthShore RailCats |
| 03/31/22 | Tri-City ValleyCats | Lujano, Jesus signed |
| 03/31/22 | Tri-City ValleyCats | Barbee, Jake placed on inactive list |
| 03/31/22 | Lake Erie Crushers | Valera, Jackson placed on inactive list |
| 03/31/22 | Lake Erie Crushers | Vivas, Julio placed on inactive list |
| 03/31/22 | Lake Erie Crushers | Abreu, Osvaldo placed on inactive list |
| 03/31/22 | Lake Erie Crushers | Aponte, Leonel placed on inactive list |
| 03/30/22 | Tri-City ValleyCats | Mercer, Matt signed |
| 03/30/22 | Sussex County Miners | Sato, Yu signed |
| 03/29/22 | Florence Yalls | Brabrand, Evan signed |
| 03/29/22 | New Jersey Jackals | Perez, Juan signed |
| 03/29/22 | New Jersey Jackals | Medina, Yeison released |
| 03/28/22 | New Jersey Jackals | Goree, Zach signed |
| 03/28/22 | Trois-Rivières Aigles | Bell, Kyle signed |
| 03/28/22 | Sussex County Miners | Robinson, Errol signed |
| 03/28/22 | Tri-City ValleyCats | Steele, Chuck signed |
| 03/28/22 | New Jersey Jackals | Mulholland, Jake acquired in trade from outside league from Lancaster Barnstormers |
| 03/27/22 | Lake Erie Crushers | Abbott, Sam signed |
| 03/27/22 | Lake Erie Crushers | Merithew, Alex signed |
| 03/27/22 | Tri-City ValleyCats | Cruz, Troy signed |
| 03/26/22 | New York Boulders | Pineda, Leudeny signed |
| 03/26/22 | Florence Yalls | Brizuela, Jose suspended |
| 03/26/22 | Florence Yalls | Brower, Jordan suspended |
| 03/25/22 | New York Boulders | Allen, Chris signed |
| 03/25/22 | Florence Yalls | Kramer, Andrew signed |
| 03/25/22 | Tri-City ValleyCats | Pena, Roberto traded to outside league to the Long Island Ducks |
| 03/25/22 | Tri-City ValleyCats | Bell, Brantley signed |
| 03/24/22 | Empire State Greys | Bernhardt, Locke signed |
| 03/24/22 | Empire State Greys | Bernhardt, Holden signed |
| 03/24/22 | New York Boulders | Kaplan, Austin signed |
| 03/24/22 | Empire State Greys | Matos, Freddie signed |
| 03/24/22 | Washington Wild Things | Lambert, Kevin acquired in trade from outside league from the Gastonia Honey Hunter |
| 03/24/22 | Washington Wild Things | Lambert, Kevin signed |
| 03/24/22 | Schaumburg Boomers | DePasquale, Parker signed |
| 03/24/22 | New York Boulders | Vancena, Jayce signed |
| 03/24/22 | Empire State Greys | Peterson, Max signed |
| 03/23/22 | Tri-City ValleyCats | Pantoja, Alexis traded to outside league to the Kane County Cougars |
| 03/22/22 | Sussex County Miners | Romano, Ramsey traded to Ottawa Titans for future considerations |
| 03/22/22 | Ottawa Titans | Romano, Ramsey acquired in trade from Sussex County Miners for future considerations |
| 03/22/22 | Washington Wild Things | Peterson, Tristan traded to outside league to the Billings Mustangs |
| 03/21/22 | Florence Yalls | Hockin, Chad signed |
| 03/21/22 | Florence Yalls | Hockin, Grant signed |
| 03/21/22 | Joliet Slammers | Gomez, Justin acquired in trade from outside league from the Missoula PaddleHeads |
| 03/21/22 | Empire State Greys | Hernandez, Franklyn signed |
| 03/21/22 | Empire State Greys | Hill, Tyler signed |
| 03/20/22 | Windy City ThunderBolts | Cruz, Aloysuis signed |
| 03/20/22 | Windy City ThunderBolts | Dunn Jr., Cordell signed |
| 03/19/22 | New Jersey Jackals | Abrams, Trevor signed |
| 03/18/22 | Sussex County Miners | Watts, Justin released |
| 03/17/22 | Joliet Slammers | Stanton, Cole signed |
| 03/17/22 | Ottawa Titans | Whatley, Kevin signed |
| 03/17/22 | Empire State Greys | Pollack, A.J. signed |
| 03/16/22 | Empire State Greys | Scott, Jordan signed |
| 03/16/22 | Empire State Greys | Kendrick, Kolton signed |
| 03/16/22 | Empire State Greys | Carling, Robbie signed |
| 03/16/22 | Empire State Greys | Benevolent, John signed |
| 03/16/22 | Tri-City ValleyCats | Hofacket, Adam signed |
| 03/15/22 | Empire State Greys | McArthur, Liam signed |
| 03/15/22 | Empire State Greys | Acevedo, Hanley signed |
| 03/15/22 | Empire State Greys | Itakura, Hiroki signed |
| 03/15/22 | Empire State Greys | Telarroja, Eric signed |
| 03/15/22 | Tri-City ValleyCats | Parks, Pavin acquired in trade from outside league from the Ogden Pioneers |
| 03/15/22 | Tri-City ValleyCats | Warren, Brac signed |
| 03/10/22 | New York Boulders | Geraci, Ernie signed |
| 03/10/22 | Ottawa Titans | Fisher, Clay signed |
| 03/10/22 | Ottawa Titans | Fukuda, Mitsuki signed |
| 03/10/22 | Trois-Rivières Aigles | Sanchez, Ricardo signed |
| 03/09/22 | Windy City ThunderBolts | Williams, Donivan traded to outside league to Gary SouthShore RailCats |
| 03/09/22 | Schaumburg Boomers | Gudino, Yeltsin placed on inactive list |
| 03/09/22 | Schaumburg Boomers | Martinez, Erik placed on inactive list |
| 03/09/22 | Washington Wild Things | Barnes, Landen signed |
| 03/09/22 | Schaumburg Boomers | Salas, William signed |
| 03/09/22 | Empire State Greys | Hernandez, Kenny signed |
| 03/05/22 | New Jersey Jackals | Almonte, Jose placed on inactive list |
| 03/05/22 | New Jersey Jackals | Valdez, Jefry placed on inactive list |
| 03/05/22 | New Jersey Jackals | Ramirez, Jose placed on inactive list |
| 03/05/22 | New Jersey Jackals | Gregorio, Joan placed on inactive list |
| 03/05/22 | New Jersey Jackals | Akatsuka, Mizuki placed on inactive list |
| 03/04/22 | Joliet Slammers | Monahan, Matt signed |
| 03/04/22 | Schaumburg Boomers | Stohr, Parker signed |
| 03/03/22 | Washington Wild Things | Fisbeck, Nate placed on inactive list |
| 03/03/22 | Washington Wild Things | James, Christian signed |
| 03/02/22 | Evansville Otters | Sensley, Steven signed |
| 03/02/22 | Lake Erie Crushers | Ellison, Karl sold to to the Philadelphia Phillies |
| 03/02/22 | Schaumburg Boomers | Claycamp, Sam signed |
| 03/02/22 | Ottawa Titans | Duncan, Tyler signed |
| 03/01/22 | Lake Erie Crushers | Begue, Brock signed |
| 03/01/22 | Windy City ThunderBolts | Johnson, Kyle sold to Chicago Cubs |
| 03/01/22 | New Jersey Jackals | Salcedo, Adryan signed |
| 03/01/22 | Ottawa Titans | Vaughn Jr., Greg released |
| 02/26/22 | Sussex County Miners | Zardon, Danny traded to outside league to the Milwaukee Milkmen |
| 02/25/22 | Lake Erie Crushers | Fuentes, Jose released |
| 02/25/22 | Lake Erie Crushers | Figueiredo, Kokko signed |
| 02/25/22 | Joliet Slammers | Daniels, Terry released |
| 02/25/22 | Joliet Slammers | Kaufman, Kyle released |
| 02/25/22 | Joliet Slammers | Mixon, Mark released |
| 02/25/22 | Washington Wild Things | Smart, Gage signed |
| 02/25/22 | Schaumburg Boomers | Snyder, Jack sold to Tampa Bay Rays |
| 02/24/22 | Sussex County Miners | Reynolds, Mikey acquired in trade from outside league Milwaukee Milkmen |
| 02/24/22 | Lake Erie Crushers | Jones, Alonzo signed |
| 02/24/22 | Lake Erie Crushers | Hubbard, Dondrei acquired in trade from outside league from Grand Junction Rockies |
| 02/24/22 | Lake Erie Crushers | Vivas, Julio signed |
| 02/24/22 | Washington Wild Things | Mink, Colt signed |
| 02/24/22 | Ottawa Titans | Fisher, Devon traded to outside league to the Idaho Falls Chukars |
| 02/24/22 | Ottawa Titans | Fernandez, Pedro released |
| 02/24/22 | Lake Erie Crushers | Betancourt, Javier traded to outside league to Staten Island Ferry Hawks |
| 02/24/22 | Ottawa Titans | Almond, Zach released |
| 02/23/22 | Schaumburg Boomers | Rivera, Isaiah sold to Minnesota Twins |
| 02/23/22 | Washington Wild Things | Kelso, Shane signed |
| 02/23/22 | Florence Yalls | Pintor, Luis suspended |
| 02/23/22 | Florence Yalls | Craport, Trevor suspended |
| 02/23/22 | Florence Yalls | Hahn, Kevin suspended |
| 02/23/22 | Tri-City ValleyCats | Sugilio, Andy placed on inactive list |
| 02/23/22 | Tri-City ValleyCats | Santana, Juan placed on inactive list |
| 02/23/22 | Tri-City ValleyCats | Parra, Olbis placed on inactive list |
| 02/23/22 | Tri-City ValleyCats | Guillen, Alexander placed on inactive list |
| 02/23/22 | Tri-City ValleyCats | Acosta, Aneudy placed on inactive list |
| 02/23/22 | Windy City ThunderBolts | Myers, Daryl signed |
| 02/22/22 | Ottawa Titans | Escorcia, Kevin signed |
| 02/22/22 | Evansville Otters | Sparks, Mitch signed |
| 02/22/22 | Evansville Otters | Bukowski, Reid signed |
| 02/22/22 | Washington Wild Things | Quillens, Bryan signed |
| 02/22/22 | Washington Wild Things | Sabol, BJ placed on inactive list |
| 02/22/22 | Lake Erie Crushers | Mulry, James traded to Sussex County Miners for LHP Gunnar Kines |
| 02/22/22 | Sussex County Miners | Mulry, James acquired in trade from Lake Erie Crushers for LHP Gunnar Kines |
| 02/22/22 | Sussex County Miners | Kines, Gunnar traded to Lake Erie Crushers for LHP James Mulry |
| 02/22/22 | Lake Erie Crushers | Kines, Gunnar acquired in trade from Sussex County Miners for LHP James Mulry |
| 02/22/22 | Sussex County Miners | Vargas, Alexander placed on inactive list |
| 02/22/22 | Sussex County Miners | Demchak, Alex placed on inactive list |
| 02/21/22 | Québec Capitales | Case, Andrew traded to outside league to the High Point Rockers |
| 02/21/22 | Evansville Otters | West, Zach signed |
| 02/21/22 | Lake Erie Crushers | Mulry, James acquired in trade from Washington Wild Things for a player to be named later |
| 02/21/22 | Washington Wild Things | Mulry, James traded to Lake Erie Crushers for a player to be named later |
| 02/21/22 | Ottawa Titans | Talamante, Jacob acquired in trade from outside league from the Missoula PaddleHeads |
| 02/21/22 | Ottawa Titans | Damon, Billy traded to outside league to the Missoula PaddleHeads |
| 02/21/22 | Québec Capitales | Sano, Carlos signed |
| 02/20/22 | Lake Erie Crushers | DeLaRosa, Bryan placed on inactive list |
| 02/19/22 | Sussex County Miners | Devenney, Ciaran signed |
| 02/18/22 | Ottawa Titans | Caro, Roberto traded to Washington Wild Things for 2022 1st round draft pick |
| 02/18/22 | Washington Wild Things | Caro, Roberto acquired in trade from Ottawa Titans for 2022 1st round draft pick |
| 02/18/22 | Washington Wild Things | Smart, Jamey signed |
| 02/18/22 | Sussex County Miners | Harris, Jawuan signed |
| 02/18/22 | Lake Erie Crushers | Johnson, Sean released |
| 02/18/22 | Evansville Otters | Phillips, Dakota signed |
| 02/17/22 | Schaumburg Boomers | Bramblett, Geoff traded to outside league to the Gastonia Honey Hunters |
| 02/17/22 | Florence Yalls | Laboy, Cristian signed |
| 02/17/22 | Ottawa Titans | Greene, Ty signed |
| 02/17/22 | Evansville Otters | Watland, Justin signed |
| 02/17/22 | Joliet Slammers | Baker, Chris signed |
| 02/17/22 | Evansville Otters | Brahms, Parker signed |
| 02/15/22 | Evansville Otters | Denton, Bryce released |
| 02/15/22 | Evansville Otters | Krane, Riley released |
| 02/15/22 | New Jersey Jackals | Drummond, Luke signed |
| 02/15/22 | New Jersey Jackals | Smith, Brennen signed |
| 02/15/22 | Evansville Otters | Pastora, Steve signed |
| 02/15/22 | New Jersey Jackals | Almonte, Jose signed |
| 02/14/22 | Ottawa Titans | Larson, Grant signed |
| 02/14/22 | Tri-City ValleyCats | Damron, Trevor Retired |
| 02/14/22 | Tri-City ValleyCats | Cline, Austin Retired |
| 02/14/22 | Sussex County Miners | Washington, Justin signed |
| 02/12/22 | Evansville Otters | Shaw, AJ signed |
| 02/12/22 | Ottawa Titans | Urbaez, Jackie signed |
| 02/12/22 | Ottawa Titans | Jacober, Dylan signed |
| 02/11/22 | Washington Wild Things | Whalen, Rob signed |
| 02/11/22 | Florence Yalls | Combs, Casey signed |
| 02/10/22 | Québec Capitales | Armsworthy, Kyle signed |
| 02/09/22 | New York Boulders | Freeman, William acquired in trade from outside league from the Missoula PaddleHeads |
| 02/09/22 | Sussex County Miners | Taylor, Chuck traded to outside league Cleburne Railroaders |
| 02/09/22 | Sussex County Miners | Groen, Gunnar acquired in trade from outside league Kansas City Monarchs |
| 02/09/22 | Evansville Otters | Callil, George signed |
| 02/08/22 | Tri-City ValleyCats | Kelly, Parker Retired |
| 02/08/22 | Tri-City ValleyCats | Hiatt, Josh Retired |
| 02/08/22 | Ottawa Titans | Loopstok, Sicnarf signed |
| 02/08/22 | Washington Wild Things | Fisbeck, Nate signed |
| 02/08/22 | Evansville Otters | Abernathy, Samson signed |
| 02/08/22 | Gateway Grizzlies | Hayes, Carter acquired in trade from Ottawa Titans |
| 02/08/22 | Ottawa Titans | Hayes, Carter traded to Gateway Grizzlies |
| 02/05/22 | Ottawa Titans | Fisher, Devon signed |
| 02/04/22 | Sussex County Miners | Watts, Justin released |
| 02/04/22 | Sussex County Miners | Cesar, Randy signed |
| 02/04/22 | Tri-City ValleyCats | Oliver, Connor signed |
| 02/04/22 | Windy City ThunderBolts | Kight, Daniel signed |
| 02/04/22 | Sussex County Miners | Castellani, Mike Retired |
| 02/04/22 | Sussex County Miners | Watts, Justin released |
| 02/03/22 | Schaumburg Boomers | Mutter, Chris signed |
| 02/03/22 | Evansville Otters | Scott, Braden sold to Toronto Blue Jays (AL) |
| 02/02/22 | Trois-Rivières Aigles | Salaman, Wilfred released |
| 02/02/22 | Trois-Rivières Aigles | Clare, Chris placed on inactive list |
| 02/02/22 | Trois-Rivières Aigles | Strunc, Jack placed on inactive list |
| 02/02/22 | Trois-Rivières Aigles | Thomas, Kyle signed |
| 02/01/22 | Québec Capitales | McAdams, Josh signed |
| 01/31/22 | Evansville Otters | Callil, George acquired in trade from outside league Sioux C (American Association) |
| 01/31/22 | Evansville Otters | Quintana, Matt traded to outside league Sioux C (American Association) |
| 01/31/22 | Evansville Otters | Felix, Justin signed |
| 01/31/22 | Evansville Otters | Holdgrafer, Tim signed |
| 01/31/22 | Sussex County Miners | Baker, John acquired in trade from outside league Chicago Dogs |
| 01/28/22 | Ottawa Titans | Grills, Evan signed |
| 01/28/22 | Tri-City ValleyCats | Lien, Connor traded to outside league Southern Maryland Blue Crabs |
| 01/27/22 | Lake Erie Crushers | Sgambelluri, Joseph signed |
| 01/26/22 | Sussex County Miners | Barmakian, Steve signed |
| 01/26/22 | Ottawa Titans | Alkire, Jack signed |
| 01/24/22 | Evansville Otters | MacDonald, Kyle signed |
| 01/24/22 | Evansville Otters | Gordon, Miles signed |
| 01/24/22 | Washington Wild Things | Balaguer, Jesus traded to outside league to the Gastonia Honey Hunters |
| 01/20/22 | Florence Yalls | Zuberer, Ray signed |
| 01/20/22 | Québec Capitales | Pittman, Riley traded to outside league to the Idaho Falls Chukars |
| 01/19/22 | Québec Capitales | Lebreux, Marc-Antoine signed |
| 01/19/22 | Joliet Slammers | Burch, Matt signed |
| 01/19/22 | Québec Capitales | Little, Webb signed |
| 01/19/22 | Evansville Otters | Gossmann, Austin signed |
| 01/14/22 | Evansville Otters | OReilly, Ryan signed |
| 01/14/22 | Evansville Otters | MacNamee, Elijah signed |
| 01/14/22 | Evansville Otters | Spring, Tyler signed |
| 01/13/22 | Florence Yalls | Brocato, Anthony signed |
| 01/13/22 | Joliet Slammers | Ogg, Kenny signed |
| 01/13/22 | Florence Yalls | Massey, Craig signed |
| 01/13/22 | Sussex County Miners | Sandoval, Ariel signed |
| 01/13/22 | Evansville Otters | Bowles, Jacob signed |
| 01/12/22 | Trois-Rivières Aigles | Bradwell, James signed |
| 01/12/22 | Trois-Rivières Aigles | Dagenais, Michel signed |
| 01/12/22 | Trois-Rivières Aigles | Hoffman, Ben signed |
| 01/12/22 | Trois-Rivières Aigles | Bélisle-Springer, Sam signed |
| 01/12/22 | Evansville Otters | Sawyer, Logan signed |
| 01/12/22 | Trois-Rivières Aigles | Macaluso, Dustyn signed |
| 01/10/22 | Ottawa Titans | Vaughn Jr., Greg signed |
| 01/06/22 | Evansville Otters | Baez, Jeffrey signed |
| 01/03/22 | Evansville Otters | Mattis, Gary signed |
| 01/03/22 | Evansville Otters | Reyes, Jomar signed |
| 01/03/22 | Ottawa Titans | Vega, Carlos traded to outside league Gary SouthShore RailCats |
| 01/03/22 | Ottawa Titans | Portorreal, Keisy traded to outside league Gary SouthShore RailCats |
| 12/29/21 | Ottawa Titans | Rolon, Kevin traded to Sussex County Miners for future considerations |
| 12/29/21 | Sussex County Miners | Rolon, Kevin acquired in trade from Ottawa Titans for future considerations |
| 12/29/21 | New Jersey Jackals | Salcedo, Edward signed |
| 12/26/21 | Sussex County Miners | Fullerton, Harry signed |
| 12/22/21 | Lake Erie Crushers | Cicci, Nick signed |
| 12/22/21 | Lake Erie Crushers | Albert, Wes signed |
| 12/16/21 | Florence Yalls | Price, Brennan signed |
| 12/16/21 | Florence Yalls | Mercado, Skylar signed |
| 12/15/21 | Ottawa Titans | Damon, Billy signed |
| 12/15/21 | Washington Wild Things | Walters, Ian signed |
| 12/14/21 | Trois-Rivières Aigles | Weinberger, Jack traded to outside league Team Kentucky -Atlantic League |
| 12/13/21 | Joliet Slammers | Rathbone, Jordan traded to outside league to the Ogden Raptors |
| 12/13/21 | Joliet Slammers | Walker, Tom traded to outside league to the Ogden Raptors |
| 12/10/21 | Ottawa Titans | Maberry, David signed |
| 12/10/21 | Schaumburg Boomers | Gudino, Yeltsin signed |
| 12/08/21 | Ottawa Titans | Westcott, Zac signed |
| 12/07/21 | Ottawa Titans | Vega, Carlos signed |
| 12/07/21 | Florence Yalls | Tripp, Johnathon traded to outside league Chicago Dogs |
| 12/06/21 | Ottawa Titans | Rolon, Kevin signed |
| 12/03/21 | Québec Capitales | Austin, Michael signed |
| 11/30/21 | Ottawa Titans | Taveras, Jose signed |
| 11/21/21 | Ottawa Titans | Walstad, Ryan signed |
| 11/20/21 | Ottawa Titans | Hayes, Carter signed |
| 11/19/21 | Ottawa Titans | Wright, A.J. signed |
| 11/13/21 | Ottawa Titans | Burica, Chris signed |
| 11/06/21 | Ottawa Titans | Sonnier, Gavin signed |
| 11/04/21 | Ottawa Titans | Curtis, Elliott signed |
| 11/04/21 | Ottawa Titans | Cable, Tanner signed |
| 11/02/21 | Florence Yalls | Diaz, Jose traded to Windy City ThunderBolts to complete a previous trade |
| 11/02/21 | Windy City ThunderBolts | Diaz, Jose acquired in trade from Florence Yalls to complete a previous trade |
| 11/01/21 | Ottawa Titans | Portorreal, Keisy signed |
| 11/01/21 | Ottawa Titans | Lacasse, Marcel signed |
| 10/28/21 | Ottawa Titans | Orozco, Rodrigo signed |
| 10/26/21 | Ottawa Titans | Caro, Roberto signed |