Caleb Graham grew up in the Tampa area of Florida and attended the University of Central Florida for his Junior and Senior year after spending his first two years of school at Florida State University. He went undrafted out of college and was picked up by the Midwest Sliders of the Frontier League. His Frontier League career was a brief one as he signed with the Angels organization in August of 2009 and sent to Orem, UT to pitch for the Owlz.

He spent four years in the Angels system making it as high as AAA for one appearance back in 2012. He spent most of last year at AA with the Arkansas Travelers compiling a record of 6-2 with a 3.83 ERA. He also made three appearances with High-A Inland Empire going record less and an ERA of 0.00 in three innings of work.