Carrillo was drafted in the 1st round of the 2005 draft by the San Diego Padres out of the University of Miami. He made it up to the #88 prospect in baseball by Baseball America in 2006. In 2005 he started out at High A Lake Elsinore before going up to AA Mobile in 2005.  He made it up to the big leagues in 2009 at age 25 with the Padres. He started three games going 1-2 with a 13.06 ERA.

He never made it back to the show and spent time in the Astros system in 2011 at AA Corpus Christi. He also spent 2012 in the Tigers organization making it as high as AA Erie. He spent 2013 with the Sugarland Skeeters of the Atlantic League making nine starts going 2-2 with 4.02 ERA. He spent 2013 with the Sugarland Skeeters of the Atlantic League making nine starts going 2-2 with 4.02 ERA.